B細胞吸引趨化因子|Human BCA-1 (CXCL13)

Synonyms :

B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand

Description :

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3 kDa protein containing 87 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

Catalog #:

300-47

Source :

E.coli

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -20⁰C. Reconstituted BCA-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20⁰C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract human B cells using a concentration range of 1.0-10.0 ng/ml.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP

PubMed Link :

BLC+AND+human+AND+Chemokine

Country of Origin :

USA