人中性粒細胞激活蛋白-2|Human NAP-2 (CXCL7)

Synonyms :

Neutrophil Activating Protein-2, CXCL7, PBP (parent molecule), CTAP-III (precursor)

Description :

NAP-2 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP). NAP-2 chemoattracts and activates neutrophils. Recombinant human NAP-2 protein is a 7.6 kDa protein containing 70 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines, and also including the ?ELR? motif common to CXC chemokines that bind to CXCR1 and CXCR2.

Catalog #:

300-14

Source :

E.coli

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -20⁰C. Reconstituted NAP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20⁰C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract human neutrophils using a concentration range of 1.0-10.0 ng/ml.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD

PubMed Link :

NAP-2+AND+human

Country of Origin :

USA