人干擾素誘導蛋白-10|Human IP-10 (CXCL10)

Synonyms :

gamma-Interferon Inducible Protein 10, CXCL10, crg-2

Description :

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.5 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.

Catalog #:

300-12

Source :

E.coli

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -20⁰C. Reconstituted IP-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20⁰C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/ml.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP

PubMed Link :

IP-10+AND+human

Country of Origin :

USA