產品名稱:Pacific Blue? 小鼠抗人 CD11b/Mac-1 抗體;Pacific Blue? Mouse Anti-Human CD11b/Mac-1
中文名稱:Pacific Blue? 小鼠抗人 CD11b/Mac-1 抗體
英文名稱:Pacific Blue? Mouse Anti-Human CD11b/Mac-1
Pacific Blue? Mouse Anti-Human CD11b/Mac-1 產品介紹:
Material Number: 558123 Alternate Name: Mac-1α, integrin αM subunit, CR3 α chain Size: 0.1 mg Concentration: 0.2 mg/ml Clone: ICRF44 (also known as 44) Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: IV M047 Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide Pacific Blue? Mouse Anti-Human CD11b/Mac-1 Description:
The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody is conjugated to Pacific Blue? under optimum conditions, and unreacted Pacific Blue? was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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