FITC Rat Anti-Mouse CD4

產品名稱:FITC 大鼠抗小鼠 CD4 抗體；FITC Rat Anti-Mouse CD4

中文名稱:FITC 大鼠抗小鼠 CD4 抗體

英文名稱:FITC Rat Anti-Mouse CD4

FITC Rat Anti-Mouse CD4 產品介紹：

Material Number: 557307
Alternate Name: Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: GK1.5
Immunogen: Mouse CTL clone V4
Isotype: Rat (LEW) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium 
azide.

The GK1.5 monoclonal antibody specifically binds to the mouse CD4 (L3T4) differentiation antigen. CD4 is expressed on most thymocytes, a 
subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells. In 
addition, CD4 has also been reported to be detectable on pluripotent hematopoietic stem cells, bone marrow myeliod and B-lymphocyte 
precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells. CD4 has also been reported to be expressed on the plasma 
membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor on the 
T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its 
association with the T-cell receptor complex and protein tyrosine kinase lck. GK1.5 mAb reportedly blocks binding of the RM4-5 (Cat. No. 
553046/553047) and H129.19 (Cat. No. 553650/553651), but not RM4-4 (Cat. No. 553055) antibodies. 

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.