產品名稱:PerCP Rat Anti-Mouse CD45 抗體;PerCP Rat Anti-Mouse CD45
中文名稱:PerCP Rat Anti-Mouse CD45 抗體
英文名稱:PerCP Rat Anti-Mouse CD45
PerCP Rat Anti-Mouse CD45 產品介紹:
Material Number: 557235 Alternate Name: Leukocyte Common Antigen (LCA), Ly-5, T200 Size: 0.1 mg Concentration: 0.2 mg/ml Clone: 30-F11 Immunogen: Mouse Thymus / Spleen Isotype: Rat (LOU) IgG2b, κ Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. PerCP Rat Anti-Mouse CD45 Description:
The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PerCP under optimum conditions, and unconjugated antibody and free PerCP were removed. Storage of PerCP conjugates in unoptimized diluent is not recommended and may result in loss of signal intensity. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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