產品名稱:FITC 小鼠抗人 CD80 抗體;FITC Mouse Anti-Human CD80
中文名稱:FITC 小鼠抗人 CD80 抗體
英文名稱:FITC Mouse Anti-Human CD80
FITC Mouse Anti-Human CD80 產品介紹:
Material Number: 557226 Alternate Name: B7-1 Size: 100 tests Vol. per Test: 20 μl Clone: L307.4 Isotype: Mouse IgG1, κ Reactivity: QC testing: Human Workshop: V B7.5 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. FITC Mouse Anti-Human CD80 Description:
Reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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