Purified Mouse Anti-Human P-glycoprotein

產品名稱:Purified 小鼠抗人 P-glycoprotein 抗體；Purified Mouse Anti-Human P-glycoprotein

中文名稱:Purified 小鼠抗人 P-glycoprotein 抗體

英文名稱:Purified Mouse Anti-Human P-glycoprotein

Purified Mouse Anti-Human P-glycoprotein 產品介紹：

Material Number: 557001
Alternate Name: MDR
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: 17F9
Isotype: Mouse IgG2b, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

Purified Mouse Anti-Human P-glycoprotein Description：

The 17F9 monoclonal antibody specifically binds to the 170-180 kDa transmembrane glycoprotein (P-glycoprotein), a product of the
multidrug resistance-1 (MDR1) gene. This glycoprotein is expressed on MDR positive cells and has been reported to be expressed on many
normal tissues, such as adrenal glands and endothelium, in the brain and skin. P-glycoprotein is known to impart drug resistance to cells by
pumping many anti-cancer drugs out of the cytoplasm. 17F9 antibody is able to partially block the binding of UIC2 antibody (another
MDR-specific monoclonal antibody). Immunoprecipitation application is reported, but not routinely tested in house.

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography