FITC Mouse Anti-Human p16 Set

產品名稱:FITC 小鼠抗人 p16 Set 抗體；FITC Mouse Anti-Human p16 Set

中文名稱:FITC 小鼠抗人 p16 Set 抗體

英文名稱:FITC Mouse Anti-Human p16 Set

FITC Mouse Anti-Human p16 Set 產品介紹：

Material Number: 556560
Reactivity: QC Testing: Human
Component: 51-13384X
Description: FITC Mouse Anti-Human p16
Size: 100 tests (1 ea)
Vol. per Test: 20 μl
Clone Name: G175-1239
Immunogen: Human p16 Recombinant Protein
Isotype: Mouse IgG1
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Component: 51-13854X-6
Description: FITC Mouse IgG1, κ Isotype Control
Size: 100 tests (1 ea)
Vol. per Test: 20 μl
Clone Name: MOPC-21
Isotype: Mouse IgG1, κ
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.


FITC Mouse Anti-Human p16 Set Description：

Cyclins and cyclin-dependent kinases (cdks) form active complexes that regulate key events during the progression of the cell cycle and are
evolutionarily highly conserved. The p16 protein has been identified as a specific inhibitor of cdk4 because it blocks cdk4 substrate
phosphorylation. p16 inhibits cdk4 dependent phosphorylation of the tumor suppressor retinoblastoma protein (Rb) and Rb related proteins,
p107 and p130. The biochemical properties of p16 suggest that it may be a tumor suppressor gene product. Recently a gene cloned from the
short arm of human chromosome 9, Multiple Tumor Suppressor 1 (MTS1) has been identified as the gene for p16]. The gene, now also known
as the CDKN2 gene, has been found to be mutated in a very high percentage of tumors, including 75% of melanoma cell lines. Alternate names
for p16 include p16-INK4, p16-INK4a, ARF, MTS1, CDKN2, CDK4l.

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.