PE Hamster Anti-Mouse Bcl-2 Set

產品名稱:PE 倉鼠抗小鼠 Bcl-2 Set 抗體；PE Hamster Anti-Mouse Bcl-2 Set

中文名稱:PE 倉鼠抗小鼠 Bcl-2 Set 抗體

英文名稱:PE Hamster Anti-Mouse Bcl-2 Set

PE Hamster Anti-Mouse Bcl-2 Set 產品介紹：

Material Number: 556537
Size: 100 tests
Reactivity: QC Testing: Mouse

PE Hamster Anti-Mouse Bcl-2 Set Description：

Programmed cell death (apoptosis) is a normal physiologic process which occurs during embryonic development as well as in maintenence of
tissue homeostasis. The apoptotic program is characterized by certain morphological features. These include changes in the plasma membrane
such as loss of membrane asymmetry and attachment, a condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA. In
the final stages, the dying cells become fragmented into “apoptotic bodies” which are rapidly eliminated by phagocytic cells without eliciting
significant inflammatory damage to surrounding cells. Members of the Bcl-2 family play a major role in regulating the cellular response to
apoptotic signals. Bcl-2 is considered to be a novel proto-oncogene because it blocks apoptosis in many cell types. Bcl-2 is thought to provide
selective survival advantage for cells by blocking apoptosis and thus may contribute to tumorigenesis. Bcl-2 is a 26 kDa intracellular, integral
membrane protein found primarily in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membrane.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.