產品名稱:Purified Mouse Anti-Ki-67
Purified Mouse Anti-Ki-67 產品介紹:
Material Number: 556003 Alternate Name: MKI67; Antigen identified by monoclonal antibody Ki-67; KIA Size: 0.1 mg Concentration: 0.5 mg/ml Clone: B56 Immunogen: Human Ki-67 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Tested in Development: Mouse Reported Reactivity: Rat, Rhesus Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. Purified Mouse Anti-Ki-67 Description:
The B56 monoclonal antibody specifically binds to the Ki-67 antigen that is expressed in the nucleus of cycling cells (G1, S, G2, M cell cycle phases). During the G0 phase, the antigen cannot be detected. During interphase of the cell cycle, it is associated with nucleolar components, and it is on the surface of the chromosomes during M phase. Ki-67 is a large protein having 2 alternatively spliced isoforms, an N-terminal forkhead-associated domain, a C-terminal domain that binds to heterochromatin proteins, and multiple phosphorylation sites, the functions of which are still unclear. Because of the strict association of Ki-67 expression with cell proliferation, anti-Ki-67 antibodies are useful for the identification, quantification, and monitoring of growing cell populations.
Store undiluted at 4°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Purified Mouse Anti-Ki-67 Suggested Companion Products:
Catalog Number Name Size Clone 555746 Purified Mouse IgG1, κ Isotype Control 0.1 mg MOPC-21 556463 Propidium Iodide Staining Solution 2 mL (none) 555816 Cell Viability Solution 100 Tests (none) 555988 FITC Goat Anti-Mouse IgG/IgM 0.5 mg Polyclonal
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