PE Mouse Anti-Human CD184

產品名稱:PE 小鼠抗人 CD184 抗體；PE Mouse Anti-Human CD184

中文名稱:PE 小鼠抗人 CD184 抗體

英文名稱:PE Mouse Anti-Human CD184

PE Mouse Anti-Human CD184 產品介紹：

Material Number: 555974
Alternate Name: CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
Size: 100 tests
Vol. per Test: 20 μl
Clone: 12G5
Isotype: Mouse (BALB/c) IgG2a, κ
Reactivity: QC Testing: Human
Workshop: VII 70204, 70305
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

PE Mouse Anti-Human CD184 Description：

The 12G5 monoclonal antibody specifically binds to CD184, also known as CXCR4 and Fusin. CD184/CXCR4 is a seven-transmembrane
domain, G-protein-linked, glycoprotein chemokine receptor. CD184 serves as a receptor for the C-X-C chemokine, SDF-1. It is expressed on a
wide variety of hematopietic cells, vascular endothelial cells and cells of the nervous system. CD184 plays a variety of roles in hematopoiesis,
vascularization and neural development. CD184 also functions as a coreceptor for infection with T-cell tropic strains of HIV-1 and as a
receptor for CD4-independent infection by some HIV isolates. The 12G5 antibody has been reported to block CD4-independent infection by
HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.