產品名稱:PE 大鼠抗人 CD49f 抗體;PE Rat Anti-Human CD49f
中文名稱:PE 大鼠抗人 CD49f 抗體
英文名稱:PE Rat Anti-Human CD49f
PE Rat Anti-Human CD49f 產品介紹:
Material Number: 555736 Alternate Name: Integrin α6 chain Size: 100 tests Vol. per Test: 20 μl Clone: GoH3 Immunogen: Mouse mammary tumor cells Isotype: Rat (SD) IgG2a, κ Reactivity:QC Testing: Human Tested in Development: Dog, Mouse, Pig Workshop: IV P55 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Rat Anti-Human CD49f Description:
Reacts with CD49f or integrin α6 chain, a 150 kDa transmembrane protein, member of extracellular matrix and cell adhesion receptor family. α6 associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to form the α6 β4 complex, also known as the laminin and kalinin receptor. CD49f is expressed mainly on T cells, monocytes, platelets, epithelial and endothelial cells, perineural cells and trophoblasts of placenta. GoH3 recognizes an extracellular epitope of integrin α6 on human, mouse and bovine cells. GoH3 has been reported to block the binding of integrin α6 to laminin P1 and E8 fragments.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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