PE Mouse Anti-Human CD117

產品名稱:PE 小鼠抗人 CD117 抗體；PE Mouse Anti-Human CD117

中文名稱:PE 小鼠抗人 CD117 抗體

英文名稱:PE Mouse Anti-Human CD117

PE Mouse Anti-Human CD117 產品介紹：

Material Number: 555714
Alternate Name: KIT ; c-Kit; SCFR; PBT: Mast/stem cell growth factor receptor
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: YB5.B8
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: V C009
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide



PE Mouse Anti-Human CD117 Description：

The YB5.B8 monoclonal antibody specifically binds to CD117. CD117, also known as c-Kit, is a 145 kDa cell-surface glycoprotein with 
tyrosine kinase activity. CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes. 
CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF). The 
interaction of c-Kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development. The ability of 
the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.