PE Mouse Anti-Human CD154

產品名稱:PE 小鼠抗人 CD154 抗體；PE Mouse Anti-Human CD154

中文名稱:PE 小鼠抗人 CD154 抗體

英文名稱:PE Mouse Anti-Human CD154

PE Mouse Anti-Human CD154 產品介紹：

Material Number: 555700
Alternate Name: CD40L
Size: 100 tests
Vol. per Test: 20 μl
Clone: TRAP1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Tested in Development: Baboon, Rhesus, Cynomolgus
Workshop: VI 6T-068
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Reacts with CD40 ligand (CD40L), a 39 kDa type II membrane glycoprotein expressed on activated T cells. CD40-CD40L interaction plays a 
very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T 
cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T 
cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells. In addition, blocking of 
CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching. It has 
been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that 
encodes CD40L

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.