FITC Mouse Anti-Human CD154

產品名稱:FITC 小鼠抗人 CD154 抗體；FITC Mouse Anti-Human CD154

中文名稱:FITC 小鼠抗人 CD154 抗體

英文名稱:FITC Mouse Anti-Human CD154

FITC Mouse Anti-Human CD154 產品介紹：

Material Number: 555699
Alternate Name: CD40L
Size: 100 tests
Vol. per Test: 20 μl
Clone: TRAP1
Isotype: Mouse IgG1 κ
Reactivity:QC Testing: Human
Tested in Development: Baboon, Rhesus, Cynomolgus
Workshop: VI 6T-068
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.



FITC Mouse Anti-Human CD154 Description：

Reacts with CD40 ligand (CD40L), a 39 kDa type II membrane glycoprotein expressed on activated T cells. CD40-CD40L interaction plays a 
very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T 
cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T 
cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells. In addition, blocking of 
CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching. It has 
been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that 
encodes CD40L. 

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.