PE Mouse Anti-Human CD95

產品名稱:PE 小鼠抗人 CD95 抗體；PE Mouse Anti-Human CD95

中文名稱:PE 小鼠抗人 CD95 抗體

英文名稱:PE Mouse Anti-Human CD95

PE Mouse Anti-Human CD95 產品介紹：

Material Number: 555674
Alternate Name: APO-1; FAS; TNFRSF6; Tumor necrosis factor receptor superfamily, member 6
Size: 100 tests
Vol. per Test: 20 μl
Clone: DX2
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Tested in Development: Baboon, Rhesus, Cynomolgus, Dog, Pig
Workshop: VI C-64
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide



PE Mouse Anti-Human CD95 Description：

The DX2 monoclonal antibody specifically binds to the human Fas antigen (also called APO-1). This 45 kDa transmembrane cell surface 
molecule was designated as CD95 at the Fifth HLDA Workshop. Fas is a member of the TNF-receptor superfamily. It is expressed on a variety 
of normal and neoplastic cells including activated T and B lymphocytes. The Fas/CD95 antigen is a polypeptide that plays a role in the 
programmed sequence of events leading to cell death, termed apoptosis. The DX2 clone specifically reacts with murine L cells, murine L1210 
leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines. 
Crosslinking CD95 with DX2 antibody delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen. 

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.