產品名稱:Purified 小鼠抗人 CD42b 抗體;Purified Mouse Anti-Human CD42b
中文名稱:Purified 小鼠抗人 CD42b 抗體
英文名稱:Purified Mouse Anti-Human CD42b
Purified Mouse Anti-Human CD42b 產品介紹:
Material Number: 555471 Size: 0.1 mg Concentration: 0.5 mg/ml Clone: HIP1 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: IV P40 Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. Purified Mouse Anti-Human CD42b Description:
The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.
Purified Mouse Anti-Human CD42b Preparation and Storage:
Store undiluted at 4°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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