產品名稱:PE-Cy?5 小鼠抗人 CD38 抗體;PE-Cy?5 Mouse Anti-Human CD38
中文名稱:PE-Cy?5 小鼠抗人 CD38 抗體
英文名稱:PE-Cy?5 Mouse Anti-Human CD38
PE-Cy?5 Mouse Anti-Human CD38 產品介紹:
Material Number: 555461 Size: 100 tests Vol. per Test: 20 μl Clone: HIT2 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: III 155 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
The HIT2 monoclonal antibody specifically binds to CD38. CD38 is a 45 kDa type II single-chain transmembrane glycoprotein present on thymocytes, activated T cells and terminally differentiated B cells (plasma cells). Other reactive cells include monocytes, macrophages, dendritic cells and some epithelial cells. The CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose. This intracellular calcium plays an important role in cell signalling pathways. Reports describe CD38 as participating in adhesion with CD31, immunoregulatory functions involving signal transduction leading to cell growth, apoptosis, and differentiation.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy5 under optimum conditions, and unconjugated antibody and free PE-Cy5 were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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