產品名稱:PE-Cy?5 小鼠抗人 CD25 抗體;PE-Cy?5 Mouse Anti-Human CD25
中文名稱:PE-Cy?5 小鼠抗人 CD25 抗體
英文名稱:PE-Cy?5 Mouse Anti-Human CD25
PE-Cy?5 Mouse Anti-Human CD25 產品介紹:
Material Number: 555433 Alternate Name: IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 Size: 100 tests Vol. per Test: 20 μl Clone: M-A251 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: IV A053 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2Rβ/CD122 and the IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy5 (formerly known as BD Cy-Chrome?) under optimum conditions, and unconjugated antibody and free PE-Cy5 were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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