APC Mouse Anti-Human CD3

產品名稱:APC 小鼠抗人 CD3 抗體；APC Mouse Anti-Human CD3

中文名稱:APC 小鼠抗人 CD3 抗體

英文名稱:APC Mouse Anti-Human CD3

APC Mouse Anti-Human CD3 產品介紹：

Material Number: 555335
Size: 100 tests
Vol. per Test: 20 μl
Clone: UCHT1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: III 471
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. 
CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop 
show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or 
anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and 
intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.