Purified NA/LE Mouse Anti-Human CD3

產品名稱:Purified NA/LE 小鼠抗人 CD3 抗體；Purified NA/LE Mouse Anti-Human CD3

中文名稱:Purified NA/LE 小鼠抗人 CD3 抗體

英文名稱:Purified NA/LE Mouse Anti-Human CD3

Purified NA/LE Mouse Anti-Human CD3 產品介紹：

Material Number: 555329
Alternate Name: CD3e; CD3E; T3E; TCRE ; T-cell surface antigen T3/Leu-4 epsilon
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: UCHT1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: III 471
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 
0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of 
protein as determined by the LAL assay.

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. 
CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop 
show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or 
anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and 
intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.