PE Rat Anti-Mouse CD3 Molecular Complex

產品名稱:PE 大鼠抗小鼠 CD3 Molecular Complex 抗體；PE Rat Anti-Mouse CD3 Molecular Complex

中文名稱:PE 大鼠抗小鼠 CD3 Molecular Complex 抗體

英文名稱:PE Rat Anti-Mouse CD3 Molecular Complex

PE Rat Anti-Mouse CD3 Molecular Complex 產品介紹：

Material Number: 555275
Size: 0.2 mg
Concentration: 0.2 mg/ml
Clone: 17A2
Immunogen: γδ TCR-positive T-T hybridoma D1
Isotype: Rat (SD) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and 
mature T lymphocytes. Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of 
accessory cells. The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11. This suggests that the 17A2 
antibody recognizes an epitope of the CD3 epsilon chain. In vivo treatment with 17A2 antibody has been reported to partially deplete T 
lymphocytes and temporarily down-modulates CD3 expression on T cells.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.