Purified NA/LE Mouse Anti-Rat CD3

產品名稱:Purified NA/LE 小鼠抗大鼠 CD3 抗體；Purified NA/LE Mouse Anti-Rat CD3

中文名稱:Purified NA/LE 小鼠抗大鼠 CD3 抗體

英文名稱:Purified NA/LE Mouse Anti-Rat CD3

Purified NA/LE Mouse Anti-Rat CD3 產品介紹：

Material Number: 554829
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: G4.18
Immunogen: PHA-stimulated rat lymph node and spleen cells
Isotype: Mouse (BALB/c) IgG3, κ
Reactivity: QC Testing: Rat
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing protein
stabilizer, no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01
EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.


Purified NA/LE Mouse Anti-Rat CD3 Description：

The G4.18 antibody reacts with the T-cell receptor-associated CD3 cell-surface antigen found on thymocytes, peripheral T lymphocytes, and
dendritic epidermal T cells. It has been reported that CD3 expression is down-regulated within 24 hours in concanavalin A-stimulated rat T
cells, and soluble mAb inhibits the allogeneic mixed-lymphocyte proliferative response and cell-mediated cytotoxicity to allogeneic target
cells. In vivo treatment with G4.18 mAb prevents cardiac and skin allograft rejection, resulting in donor-specific tolerance. Pre-incubation of
splenocytes with the alternate anti-rat CD3 monoclonal antibody, 1F4 (Cat. No. 556970), blocks staining with mAb G4.18.

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.