PE Hamster Anti-Mouse CD28

產品名稱:PE 倉鼠抗小鼠 CD28 抗體；PE Hamster Anti-Mouse CD28

中文名稱:PE 倉鼠抗小鼠 CD28 抗體

英文名稱:PE Hamster Anti-Mouse CD28

PE Hamster Anti-Mouse CD28 產品介紹：

Material Number: 553297
Size: 0.2 mg
Concentration: 0.2 mg/ml
Clone: 37.51
Immunogen: Mouse EL-4 (T-cell lymphoma) Cells
Isotype: Syrian Hamster IgG2, λ1
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T 
cells, and at even lower density on NK cells. The expression of CD28, in splenocytes and thymocytes, has been reported to increase after 
activation. CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast 
cells. It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes. CD28 is a costimulatory receptor; 
its ligands include CD80 (B7-1) and CD86 (B7-2). The 37.51 mAb augments proliferation and cytokine production by activated T and NK 
cells and can provide a costimulatory signal for CTL induction. There is considerable evidence that CD28 is a costimulatory receptor involved 
in many, but not all, T cell-dependent immune responses.

PE Hamster Anti-Mouse CD28 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.