FITC Mouse Anti-Pig CD8a

產品名稱:FITC 小鼠抗豬 CD8a 抗體；FITC Mouse Anti-Pig CD8a

中文名稱:FITC 小鼠抗豬 CD8a 抗體

英文名稱:FITC Mouse Anti-Pig CD8a

FITC Mouse Anti-Pig CD8a 產品介紹：

Material Number: 551303
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: 76-2-11
Immunogen: dd miniature swine thymocytes
Isotype: Mouse (BALB/c) IgG2a, κ
Reactivity: QC Testing: Porcine
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


FITC Mouse Anti-Pig CD8a Description：

The 76-2-11 (also known as clone PT8) antibody reacts with an epitope on the CD8α chain, a 35-kDa antigen expressed on thymocytes, 
peripheral T lymphocytes, and NK cells. The CD8 molecule can exist as a 70 kDa homodimer, composed of α chains, or heterodimer, 
composed of an α and β chain. Cells which express the CD8αα homodimer display dimmer staining with mAb 76-2-11 than CDαβ-expressing 
cells. The 76-2-11 mAb does not cross-react with human or bovine cells. Two peripheral CD8+ T-cell populations can be distinguished in the 
pig: CD8-bright CD4- CTL effectors/precursors and CD8-dull CD4+ T-helper lymphocytes. Pig NK cells express CD8 (dull staining), CD2, 
MHC class II, LFA-1, and asialo-GM1, but not CD3, CD4, CD5, or CD6. mAb 76-2-11 has been reported to partially inhibit in vitro cytotoxic 
activity of PBL to allogeneic leukocytes, but not NK-cell-mediated lysis, and to deplete CD8+ T cells in vivo. This clone was clustered as 
anti-CD8a at the First International Swine CD workshop.

FITC Mouse Anti-Pig CD8a Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.