重組人 EphrinB1 / EFNB1 蛋白|Ephrin-B1 / EFNB1 / ELK-L Protein|產品詳情|現貨

EFNB1蛋白產品信息
產品名稱：重組人 EphrinB1 / EFNB1 蛋白|Ephrin-B1 / EFNB1 / ELK-L Protein|產品詳情|現貨
別名: EFNB1,RP3-496G1.1, CFND, CFNS, EFL3, EPLG2, Elk-L, LERK2,
Protein Construction: A DNA sequence encoding the human EFNB1 (NP_004420.1) extracellular domain (Met 1- Gly 232) was fused with a polyhistidine tag at the C-terminus.
種屬: Human
表達宿主: Human Cells

EFNB1蛋白質控指標
純度: >95% as determined by SDS-PAGE. SDS-PAGE:
內**: < 1.0 EU per μg of the protein as determined by the LAL method.
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Leu 28
分子量: The recombinant human EFNB1 consists of 221 amino acids and predicts a molecular mass of 24.5 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh EFNB1 is approximately 38 KDa due to glycosylation.
緩沖液: 
Lyophilized from 0.2μm filtered solution of PBS, pH7.4
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
 
EFNB1蛋白使用指南
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted and be used as soon as possible. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
EFNB1 Protein Description
The ephrins (Eph) and Eph receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. All ephrins share a conserved extracellular sequence, which most likely corresponds to the receptor-binding domain. In molecular biology, ephrins and Eph receptors are components of cell signaling pathways involved in animal development, and implicated in some cancers. Ephrin-B1, also known as LERK-2, ELK-L, EFL-3, Cek5-L, and STRA-1, is a member of the ephrin ligand family which binds members of the Eph receptor family. Ephrin-B1 has been shown to bind EphA3, EphB1, EphB2, EphB3, and EphB4. The extracellular domains of human and mouse ephrin-B1 share 94% amino acid identity.
EFNB1 Protein Related Products & Topics
參考文獻
Cerretti, DP. et al., 1995, Mol. Immunol. 32 (16): 1197-205.
Gale, NW. et al.,1996, Neuron.17 (1): 9-19.
Flanagan, J. et al., 1998, Annual Review of Neuroscience. 21: 309-45.
Holder, N. et al., 1999,  Development. 126 (10): 2033-44.
Wilkinson, DG. et al., 2001, Nat. Rev. Neurosci. 2 (3): 155-64.
Murai, KK. et al., 2003, Journal of Cell Science. 116 (Pt 14): 2823-32.

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