重組人 CCL27 / CTACK 蛋白|Chemokine (C-C motif) ligand 27 Protein|技術資料|價格

cCCL27 / CTACK蛋白產品信息
產品名稱：重組人 CCL27 / CTACK 蛋白|Chemokine (C-C motif) ligand 27 Protein|技術資料|價格
別名: CCL27, ILC, SCYA27
表達方式: A DNA sequence encoding the human CCL27 (Q9Y4X3) (Phe25-Gly112) was expressed with a polyhistidine tag at the N-terminus.
種屬: Human
表達宿主: E.coli

CCL27 / CTACK Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: Please contact us for more information.
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: His
分子量: The recombinant human CCL27 consists of  104 amino acids and predicts a molecular mass of 12.2 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile 30% acetonitrile, 0.1% TFA.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CCL27 / CTACK Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CCL27 / CTACK蛋白背景綜述
CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphocytes. CCL27 may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27 plays a pivotal role in establishing the inflammatory infiltrate characteristic for common inflammatory skin diseases. Through binding to the chemokine receptor 10 (CCR10), CCL27 mediates inflammation by promoting lymphocyte migration into the skin.
參考文獻
Morales. et al., 1999, Proc Natl Acad Sci. 96: 14470-5.
Homey. et al., 2002, J Immunol. 164: 3465-70.
Ishikawa-Mochizuki. et al., 1999, FEBS Lett. 460: 544-8.

包裝：25ug

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