CD48 / BCM1 / SLAMF2蛋白產品信息
別名: CD48, Bcm-1
表達方式:
A DNA sequence encoding the rat CD48 (P10252)(Met1-Arg216) was expressed, fused with a polyhistidine tag at the C-terminus.
種屬: Rat
表達宿主: Human Cells
CD48 / BCM1 / SLAMF2 Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Phe 23
分子量:
The recombinant rat CD48 comprises 205 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of the recombinant protein is approximately 38-43 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
CD48 / BCM1 / SLAMF2 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CD48 / BCM1 / SLAMF2蛋白背景綜述
CD48, also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 has a striking array of biological functions, among them adhesion, pathogen recognition, cellular activation, and cytokine regulation. CD48 performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses. In rodents, CD48 is the ligand for CD2 whereas in humans, CD58 is the ligand for CD2. CD48 has a high degree of sequence homology to CD58 (LFA-3), and Mouse CD48 shares approximately 50% aa sequence identity with human CD48.
參考文獻
Wong YW. et al., 1990, J Exp Med. 171: 2115-30.
Ianelli CJ. et al., 1997, J Immunol. 159 (8): 3910-20.
Ianelli CJ. et al., 1998, J Biol Chem. 273: 23367-75.
Loertscher, R. et al., 2002, Transpl Immunol. 9: 93-6.
Assarsson E. et al., 2005, J Immunol. 175: 2045-9.
Bhat R. et al., 2006, J Leukocyte Biol. 79: 417-24.
Munitz A. et al., 2007, Recent Pat Inflamm Allergy Drug Discov. 1 (1): 9-12.
規格：50ug
關 鍵 詞：Rat CD48 / BCM1 / SLAMF2 Protein,產品詳情,價格，實驗室耗材，生化試劑，上海創賽，博飛美科，實驗儀器，廠家
CANSPEC品質提供的Rat CD48 / BCM1 / SLAMF2 Protein|產品詳情|價格性能**，其優良的品質滿足您不同實驗的多種需求。
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