ORM2 Protein|ORM2蛋白質|技術資料|廠家價格

ORM2蛋白產品信息

別名: ORM2, AGP2
表達方式: 
A DNA sequence encoding the human ORM2 (P19652) (Met1-Ser201) was expressed with a polyhistidine tag at the C-terminus.
種屬: Human
表達宿主: Human Cells

ORM2 Protein QC Testing

純度: > 90% as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Gln 19
分子量: 
The recombinant human ORM2 consists of  194 amino acids and predicts a molecular mass of 23.1 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

ORM2 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

ORM2蛋白背景綜述

ORM2 is a member of the calycin superfamily, lipocalin family. Lipocalins are characterized by  limited regions of sequence homology and a common tertiary structure architecture. They are associated with many biological processes and can be found in gram negative bacteria, vertebrate cells, and invertebrate cells, and in plants. Lipocalins transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. ORM2 functions as transport protein in the blood stream. It is expressed by the liver and secreted in plasma. It appears to function in modulating the activity of the immune system during the acute-phase reaction. It binds various hydrophobic ligands in the interior of its beta-barrel domain. It also binds synthetic drugs and influences their distribution and availability.

參考文獻

Lee MT. et al., 2009, Pharmacogenomics. 10 (12): 1905-11.
Davila S. et al., 2010, Genes Immun. 11 (3): 232-8.
Zhang X. et al., 2012, PLoS One. 7 (2): e31868.

規格：50ug

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