GBP-2 / GBP2蛋白產品信息
別名: GBP2 表達方式: A DNA sequence encoding the human GBP2 (AAH73163.1) (Met1-Cys588) was expressed with a polyhistidine tag at the C-terminus. 種屬: Human 表達宿主: Human Cells GBP-2 / GBP2 Protein QC Testing
純度: > 90% as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Met 分子量: The recombinant human GBP2 consists of 599 amino acids and predicts a molecular mass of 68.3 KDa. It migrates as an approximately 62 KDa band in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. GBP-2 / GBP2 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. GBP-2 / GBP2蛋白背景綜述
GBP-2 is a member of the guanylate-binding protein (GBP) family. As GTPases induced by IFN-gamma (Interferon-inducible GTPase), GBPS are key to the protective immunity against microbial and viral pathogens. GBPS are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interferons that have antiviral effects and inhibit tumor cell proliferation. 參考文獻
Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903. Wistow G. et al., 2002, Mol Vis. 8: 205-20. Neun R et al., 1996, FEBS Lett. 390 (1): 69-72. 規格:20ug 關 鍵 詞:GBP-2 / GBP2 Protein,現貨,廠家,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器
CANSPEC品質提供的GBP-2 / GBP2 Protein| 現貨|廠家性能**,其優良的品質滿足您不同實驗的多種需求。
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