Rat CD302 / CLEC13A Protein|實驗說明|價格|廠家

CD302 / CLEC13A蛋白產品信息

別名: CD302, Clec13a
表達方式: 
A DNA sequence encoding the rat CD302 (Met1-His165) was expressed with a polyhistidine tag at the C-terminus.
種屬: Rat
表達宿主: Human Cells

CD302 / CLEC13A Protein QC Testing

純度: (49.5+41.9)% as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Asp 21
分子量: 
The recombinant rat CD302 comprises 156 amino acids and predicts a molecular mass of 18.1 kDa. The apparent molecular mass of  the recombinant protein is approximately 18 and 22 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CD302 / CLEC13A Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CD302 / CLEC13A蛋白背景綜述

CD302, also known as C-type lectin domain family 13 member A (CLEC13A), or Type I transmembrane C-type lectin receptor DCL-1, is an unconventional C-type lectin that may play roles not only in endocytosis/phagocytosis but also in APC adhesion and migration. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling.

參考文獻

Skinnider B. et al., 2002, Blood. 99 (12): 4283-97.
Kato M. et al., 2007, J Immunol. 179 (9): 6052-63.
 
規格：20ug

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