LMAN2L Protein|LMAN2L蛋白質|價格|廠家|參數

LMAN2L蛋白產品信息

別名: LMAN2L, VIPL
表達方式: 
A DNA sequence encoding the human LMAN2L (NP_110432.1)(Met1-Ala304) was expressed with the Fc region of human IgG1 at the C-terminus.
種屬: Human
表達宿主: Human Cells

LMAN2L Protein QC Testing

純度: > 80 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Gly 45
分子量: 
The recombinant human LMAN2L/Fc is a disulfide-linked homodimer. The reduced monomer comprises 501 amino acids and has a predicted molecular mass of 56.9 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

LMAN2L Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

LMAN2L蛋白背景綜述

LMAN2L contains 1 L-type lectin-like domain. LMAN2L gene contains 15 distinct gt-ag introns and may be modulated by acetylation; phosphorylation, as detailed at PhosphoSite. Alternative splicing produces 2 isoforms of the human protein. LMAN2L localize in various compartments. It is highly expressed in skeletal muscle and kidney, and its intermediate expression levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung. LMAN2L may be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. It also may function as a regulator of ERGIC-53.

參考文獻

Hartley JL. et al., 2001, Genome Res. 10 (11): 1788-95.
Suzuki Y. et al., 1997, Gene. 200 (1-2) :149-56.
Maruyama K. et al., 1994, Gene. 138 (1-2): 171-4.

規格：20ug

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