Rat CLEC14A / EGFR-5 Protein |價格|廠家|現貨

CLEC14A / EGFR-5蛋白產品信息

別名: CLEC14A
表達方式: 
A DNA sequence encoding the rat CLEC14A (Met1-Thr398) was expressed with the Fc region of human IgG1 at the C-terminus.
種屬: Rat
表達宿主: Human Cells

CLEC14A / EGFR-5 Protein QC Testing

純度: (75.4+12.7 )% as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Glu 22
分子量: 
The recombinant rat CLEC14A/Fc is a disulfide-linked homodimer. The reduced monomer comprises 618 amino acids and has a predicted molecular mass of 67.6 kDa. The apparent molecular mass of the protein is approximately 110 and 37 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CLEC14A / EGFR-5 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CLEC14A / EGFR-5蛋白背景綜述

C-type lectin domain family 14 member A, also known as Epidermal growth factor receptor 5 and CLEC14A, is a member of the C-type lectin domain (CTLD) family that contains one c-type lectin domain and one EGF-like domain. Mouse CLEC14A is a single-pass type I  membrane protein. Members of the C-type lectin domain (CTLD) superfamily are metazoan proteins functionally important in glycoprotein metabolism, mechanisms of multicellular integration and immunity. They share a common fold and are involved in a variety of functions, such as generalized defense mechanisms against foreign agents, discrimination between healthy and pathogen-infected cells, and endocytosis and blood coagulation. Genome-level studies on human, elegans and melanogaster demonstrated almost complete divergence among invertebrate and mammalian families of CTLD-containing proteins (CTLDcps). The vertebrate CTLDcp families were essentially formed early in vertebrate evolution and are completely different from the invertebrate families. The composition of the CTLDcp superfamily in fish and mammals suggests that large scale duplication events played an important role in the evolution of vertebrates.

參考文獻

Carninci P. et al., 1999, Methods Enzymol. 303: 19-44.
Ebner S. et al., 2003, Proteins. 53 (1): 44-55.
Zelensky AN. et al., 2004, BMC Genomics. 5 (1): 51.
Carninci P. et al., 2005, Science. 309: 1559-63.

規格：20ug

關 鍵 詞：Rat CLEC14A / EGFR-5 Protein ,價格,廠家,現貨，實驗室耗材，生化試劑，上海創賽，博飛美科，實驗儀器，廠家

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