Rat CSF2RB Protein|技術資料|現貨

CSF2RB蛋白產品信息

別名: CSF2Rb, Csf2rb1
表達方式: 
A DNA sequence encoding the rat CSF2Rb (Met1-Trp440) was expressed with the Fc region of human IgG1 at the C-terminus.
種屬: Rat
表達宿主: Human Cells

CSF2RB Protein QC Testing

純度: (24.0+69.6 )% as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: His 23
分子量: 
The recombinant rat CSF2Rb/Fc is a disulfide-linked homodimer. The reduced monomer comprises 659 amino acids and has a predicted molecular mass of 75.1 kDa. The apparent molecular mass of the protein is approximately 123 and 89 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CSF2RB Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CSF2RB蛋白背景綜述

Colony stimulating factor 2 receptor, beta, low-affinity, also known as Cytokine receptor common subunit beta, CSF2RB, CDw131, and CD131, is a single-pass type I  membrane protein which belongs to the type I  cytokine receptor family and Type 4 subfamily. It is a 897 amino acid protein which the sequence is further processed into a mature form. The cytokine receptor is a heterodimer of an alpha and a beta subunit, and this beta subunit (CD131) is also the common and high affinity receptor to the interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. It contains two fibronectin type-III domains. The WSXWS motif of CD131 appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif of CD131 is required for JAK interaction and/or activation.

參考文獻

Mulhern TD. et al., 2000, J Mol Biol. 297: 989-1001.
Carr PD. et al., 2001, Cell. 104: 291-300.
Carr PD. et al., 2006, Acta Crystallogr. F 62: 509-13.
Selleri S. et al., 2008, J Transl Med. 6 : 17.

規格：50ug

關 鍵 詞：Rat CSF2RB Protein,技術資料,現貨，實驗室耗材，生化試劑，上海創賽，博飛美科，實驗儀器，廠家

CANSPEC品質提供的Rat CSF2RB Protein|技術資料|現貨性能**，其優良的品質滿足您不同實驗的多種需求。

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