Serglycin / SRGN蛋白產品信息
別名: SRGN, PRG, PRG1 表達方式: A DNA sequence encoding the human SRGN (CAA34900.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus. 種屬: Human 表達宿主: Human Cells Serglycin / SRGN Protein QC Testing
純度: > 95% as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Tyr 28 分子量: The recombinant human SRGN consists of 142 amino acids and predicts a molecular mass of 16.1 KDa. It migrates as an approximately 57 KDa band in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. Serglycin / SRGN Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. Serglycin / SRGN蛋白背景綜述
SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. 參考文獻
Hatton MN. et al., 1985, Biochem J. 230 (3): 817-20. Schick BP. et al., 1995, J Cell Physiol. 165 (1): 96-106. Kato S. et al., 1995, Gene. 150 (2): 243-50. 規格:50ug 關 鍵 詞:Serglycin / SRGN Protein,技術資料,價格,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
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