B3GALTL Protein|B3GALTL蛋白質|參數|產品詳情

B3GALTL蛋白產品信息

別名: B3GALTL, B3GTL
表達方式: 
A DNA sequence encoding the human B3GALTL (Ser29-Phe494) was expressed with an N-terminal polyhistidine tag.
種屬: Human
表達宿主: Human Cells

B3GALTL Protein QC Testing

純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: His
分子量: 
The recombinant human B3GALTL comprises 486 amino acids and has a predicted molecular mass of 55.4 kDa. The apparent molecular mass of the protein is approximately 54 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

B3GALTL Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

B3GALTL蛋白背景綜述

B3GALTL is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. B3GALTL is a type II membrane protein. Defects in B3GALTL gene are a cause of Peters-plus syndrome (PPS). As an O-fucosyltransferase, B3GALTL transfers glucose toward fucose with a beta-1,3 linkage. It specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.

參考文獻

Heinonen TY. et al., 2003, Biochem Biophys Res Commun. 309 (1): 166-74.
Sato T. et al., 2006, Glycobiology. 16 (12): 1194-206.
Kozma K. et al., 2006, J Biol Chem. 281 (48): 36742-51.

規格：20ug

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