Mouse IL12B / IL-12B Protein|廠家現貨|參數

IL12B / IL-12B蛋白產品信息

別名: IL12B
表達方式: 
A DNA sequence encoding the mouse IL12B (P43432) (Met 1-Ser 335) was expressed with six amino acids (LEVLFQ) at the C- terminus.
種屬: Mouse
表達宿主: Human Cells

IL12B / IL-12B Protein QC Testing

純度: > 85 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Met 23
分子量: 
The recombinant mouse IL12B consists of 320 amino acids and has a calculated molecular mass of 36.6 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

IL12B / IL-12B Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IL12B / IL-12B蛋白背景綜述

Interleukin 12 (IL-12), also known as NKSF or CLMF, is a disulfide-linked heterodimeric cytokine composed of a 35kDa subunit P35 and a 40kDa subunit P40, also designated as IL-12A and IL-12B. IL-12 is predominantly produced by macrophages and B lymphocytes and plays an important role in the activities of natural killer cells and T lymphocytes. It is involved in the differentiation and development of Th1 cells, enhancement of natural killer cells’ cytolytic function and mitogenic effects, as well as induction of IFN-gamma during which it can synergize with other IFN-gamma inducers. A large excess of monomeric IL-12B is also secreted by the cells producing IL-12, and exhibits no demonstrable biological activity. Overexpression of IL-12B has been shown to be associated with the pathogenesis of multiple sclerosis.

參考文獻

Ling P. et al., 1995, J Immunol. 154: 116-27.
Thierfelder WE. et al., 1996, Nature. 382: 171-4.
Kato K. et al., 1996, Proc Natl Acad Sci. 93: 9085-89.
Kim JH. et al., 1997, Clin Exp Immunol. 108: 243-50.

規格：20ug

關 鍵 詞：Mouse IL12B / IL-12B Protein,廠家現貨,參數，實驗室耗材，生化試劑，上海創賽，博飛美科，實驗儀器，廠家

CANSPEC品質提供的Mouse IL12B / IL-12B Protein|廠家現貨|參數性能**，其優良的品質滿足您不同實驗的多種需求。

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