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    產品資料

    Mouse M-CSF / CSF-1 Protein|技術資料|現貨

    產品名稱: Mouse M-CSF / CSF-1 Protein|技術資料|現貨
    產品型號: C86-511-12
    產品展商: 博飛美科
    產品文檔: 無相關文檔

    簡單介紹

    Mouse M-CSF / CSF-1 Protein|技術資料|現貨由上海創賽科學儀器有限公司品質提供,可查詢Mouse M-CSF / CSF-1 Protein價格。上海創賽科學儀器有限公司是專業**試劑生產及供應商,其優良的品質滿足您不同實驗的多種需求,歡迎撥打4006087598洽談選購,更多產品詳情請登錄www.getprovidencehotels.com


    Mouse M-CSF / CSF-1 Protein|技術資料|現貨  的詳細介紹

    M-CSF / CSF-1蛋白產品信息

    別名: CSF1, Csfm
    表達方式: 
    A DNA sequence encoding the mouse CSF1 (P07141-1) (Met1-Glu262) was expressed with a C-terminal polyhistidine tag.
    種屬: Mouse
    表達宿主: Human Cells

    M-CSF / CSF-1 Protein QC Testing

    純度: > 95 % as determined by SDS-PAGE SDS-PAGE
    內**: < 1.0 EU per μg of the protein as determined by the LAL method
    穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
    預測N端: Lys 33
    分子量: 
    The recombinant mouse CSF1 comprises 241 amino acids and has a predicted molecular mass of 27.4 kDa. The apparent molecular mass of the protein is approximately 40-55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
    緩沖液: Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    Please contact us for any concerns or special requirements.

    M-CSF / CSF-1 Protein Usage Guide

    儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
    Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

    M-CSF / CSF-1蛋白背景綜述

    Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.

    參考文獻

    Pandit J. et al., 1992, Science. 258: 1358-62.
    Tokai M. et al., 2000, J Bacteriol. 182 (10): 2865-8.
    Fan X. et al., 2001, Am J Physiol Endocrinol Metab. 280 (1): E103-11.
    Frangogiannis NG. et al., 2003, Am J Physiol Heart Circ Physiol. 285 (2): H483-92.
    Cupp JS. et al., 2007, Am J Surg Pathol. 31 (6): 970-6.

    規格:10ug

    關 鍵 詞:Mouse M-CSF / CSF-1 Protein,技術資料,現貨,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家

    CANSPEC品質提供的Mouse M-CSF / CSF-1 Protein|技術資料|現貨性能**,其優良的品質滿足您不同實驗的多種需求。

    本產品由上海創賽品質提供,歡迎咨詢國內免費服務專線:400-608-7598,更多產品信息請登錄www.getprovidencehotels.com 或 www.4006087598.com

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