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    產品資料

    SIGLEC5 Protein|SIGLEC5蛋白質|現貨|產品詳情

    產品名稱: SIGLEC5 Protein|SIGLEC5蛋白質|現貨|產品詳情
    產品型號: C86-117-98
    產品展商: 博飛美科
    產品文檔: 無相關文檔

    簡單介紹

    SIGLEC5 Protein|SIGLEC5蛋白質|現貨|產品詳情由上海創賽科學儀器有限公司品質提供,可查詢SIGLEC5 Protein價格。上海創賽科學儀器有限公司是專業**試劑生產及供應商,其優良的品質滿足您不同實驗的多種需求,歡迎撥打4006087598洽談選購,更多產品詳情請登錄www.getprovidencehotels.com


    SIGLEC5 Protein|SIGLEC5蛋白質|現貨|產品詳情  的詳細介紹

    SIGLEC5蛋白產品信息

    別名: SIGLEC5, CD33L2, OBBP2
    表達方式: 
    A DNA sequence encoding the human SIGLEC5 (O15389) (Met1-Thr 434) was expressed with six amino acids (LEVLFQ) at the C- terminus was expressed and purified.
    種屬: Human
    表達宿主: Human Cells

    SIGLEC5 Protein QC Testing

    純度: > 85% as determined by SDS-PAGE SDS-PAGE
    內**: < 1.0 EU per μg of the protein as determined by the LAL method
    穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
    預測N端: Glu 17
    分子量: 
    The recombinant human SIGLEC5 consists of  425 amino acids and predicts a molecular mass of 47.2 KDa. It migrates as an approximately 67 KDa band in SDS-PAGE under reducing conditions.
    緩沖液: Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    Please contact us for any concerns or special requirements.

    SIGLEC5 Protein Usage Guide

    儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
    Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

    SIGLEC5蛋白背景綜述

    SIGLEC5 is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. SIGLEC5 also contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. It is highly expressed in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. As a putative adhesion molecule, SIGLEC5 mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

    參考文獻

    Angata T. et al., 2006, FASEB J. 20 (12): 1964-73.
    Avril T. et al., 2005, J Biol Chem. 280 (20): 19843-51.
    Erickson-Miller CL. et al., 2003, Exp Hematol. 31 (5): 382-8.

    規格:50ug

    關 鍵 詞:SIGLEC5 Protein,SIGLEC5蛋白質,現貨,產品詳情,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家

    CANSPEC品質提供的SIGLEC5 Protein|SIGLEC5蛋白質|現貨|產品詳情性能**,其優良的品質滿足您不同實驗的多種需求。

    本產品由上海創賽品質提供,歡迎咨詢國內免費服務專線:400-608-7598,更多產品信息請登錄www.getprovidencehotels.com 或 www.4006087598.com

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