CLM-9 / TREM4 / CD300LG蛋白產品信息
別名: CD300LG, CLM9, TREM4 表達方式: A DNA sequence encoding the human CD300LG (AAH25395.1)(Met1-Arg247) was expressed with six amino acids (LEVLFQ) at the C- terminus was expressed and purified. 種屬: Human 表達宿主: Human Cells CLM-9 / TREM4 / CD300LG Protein QC Testing
純度: > 95% as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Leu 19 分子量: The recombinant human CD300LG consists of 236 amino acids and predicts a molecular mass of 25.5 KDa. It migrates as an approximately 61-66 KDa band in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. CLM-9 / TREM4 / CD300LG Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. CLM-9 / TREM4 / CD300LG蛋白背景綜述
CLM-9, also known as TREM4, is a member of the CD300 -like (CD300L) family. CLM-9 is widely expressed on hematopoietic cells. All CD300L proteins are type I cell surface glycoproteins that contain a single immunoglobulin (Ig) V-like domain. It is a receptor which may mediate L-selectin-dependent lymphocyte rollings. CLM-9 binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. CLM-9 gene encodes the human and murine protein. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM. 參考文獻
Clark GJ. et al., 2009, Immunobiology. 214 (9-10): 730-6. Engel K. et al., 2012, J Inherit Metab Dis. 35 (1): 133-40. Lamesch P. et al., 2007, Genomics. 89 (3): 307-15. 規格:50ug 關 鍵 詞:CLM-9 / TREM4 / CD300LG Protein,產品詳情,價格,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
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