TSPAN8 / Tetraspanin 8 / TM4SF3蛋白產品信息
別名: TSPAN8, TM4SF3 表達方式: A DNA sequence encoding the human TSPAN8 (P19075) (Lys110-Asn205) was expressed with an N-terminal polyhistidine tag. 種屬: Human 表達宿主: Human Cells TSPAN8 / Tetraspanin 8 / TM4SF3 Protein QC Testing
純度: (87.8+10.7) % as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: His 分子量: The recombinant human TSPAN8 comprises 116 amino acids and has a predicted molecular mass of 13.4 kDa. The apparent molecular mass of the protein is approximately 17 and 13 kDa in SDS-PAGE under reducing conditions due to glycosylation. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. TSPAN8 / Tetraspanin 8 / TM4SF3 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. TSPAN8 / Tetraspanin 8 / TM4SF3蛋白背景綜述
TSPAN8, also known as tetraspanin 8 and TM4SF3, is a member of the transmembrane 4 superfamily. Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. They mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN8 gene is expressed in different carcinomas. TSPAN8 is a cell surface glycoprotein that is known to complex with integrins. TSPAN8 is also known to efficiently induce angiogenesis in tumors and tumor-free tissues. However, little information exists on exosome-endothelial cell (EC) interactions or the proangiogenic role of tetraspanins. TSPAN8 contributed to a selective recruitment of proteins and mRNA into exosomes, including CD106 and CD49d. 參考文獻
Szala S. et al., 1990, Proc Natl Acad Sci. 87 (17): 6833-7. Berditchevski F. et al., 2002, J Cell Sci. 114 (23): 4143-51. Maruyama K. et al., 1994, Gene. 138 (1-2): 171-4. Nazarenko I. et al., 2010, Cancer Res. 70 (4): 1668-78. 規格:10ug 關 鍵 詞:TSPAN8 / Tetraspanin 8 / TM4SF3 Protein,技術資料,現貨,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
CANSPEC品質提供的TSPAN8 / Tetraspanin 8 / TM4SF3 Protein|技術資料|現貨性能**,其優良的品質滿足您不同實驗的多種需求。
本產品由上海創賽品質提供,歡迎咨詢國內免費服務專線:400-608-7598,更多產品信息請登錄www.getprovidencehotels.com 或 www.4006087598.com
國內免費服務專線:400 608 7598(據說天才可以在15秒內記住我們的免費電話哦^_^)
服務升級,全新企業QQ為您服務,企業QQ號:4006087598
創賽官網升級為創賽優選商城,請移步www.canspec.cn注冊登錄,新用戶注冊送1000元現金券
滬公網安備 31011402005168號