CD160蛋白產品信息
別名: CD160 表達方式: A DNA sequence encoding the cynomolgus CD160 (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus. 種屬: Cynomolgus 表達宿主: Human Cells CD160 Protein QC Testing
純度: (70+22.5)% as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Gly 25 分子量: The recombinant cynomolgus CD160 comprises 145 amino acids and has a calculated molecular mass of 16.3 KDa. The apparent molecular mass of it is approximately 25 and 22 KDa respectively in SDS-PAGE. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. CD160 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. CD160蛋白背景綜述
CD160 antigen, also known as Natural killer cell receptor BY55 and CD160, is a cell membrane protein which contains one?Ig-like V-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and small intestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD160+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness. 參考文獻
Barakonyi A. et al., 2004, J Immunol.173 (9): 5349-54. Rabot M. et al., 2006, Transpl Immunol. 17 (1): 36-8. Abecassis S. et al., 2007, J Invest Dermatol. 127?(5): 1161-6. Giustiniani J.?et al., 2007, J Immunol. 178 (3): 1293-300. 規格:50ug 關 鍵 詞:Cynomolgus CD160 Protein,廠家現貨,報價,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
CANSPEC品質提供的Cynomolgus CD160 Protein|廠家現貨|報價性能**,其優良的品質滿足您不同實驗的多種需求。
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