Interferon alpha-B / IFNA8蛋白產品信息
別名: IFNA8 表達方式: A DNA sequence encoding the cynomolgus IFNA8(G7PS89) (Met1-Glu189) was expressed with Fc region of mouse IgG at the C-terminus. 種屬: Cynomolgus 表達宿主: Human Cells Interferon alpha-B / IFNA8 Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Cys 24 分子量: The recombinant cynomolgus IFNA8 is a disulfide-linked homodimer. The reduced monomer comprises 400 amino acids and has a calculated molecular mass of 46 KDa.The apparent molecular mass of the protein is approximately 48 KDa respectively in SDS-PAGE. 緩沖液: Lyophilized from sterile PBS, PH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. Interferon alpha-B / IFNA8 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. Interferon alpha-B / IFNA8蛋白背景綜述
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumorcells. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They also allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. Interferons also activate immune cells, such as natural killer cells and macrophages. They increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes. They also increase the ability of uninfected host cells to resist new infection by virus. Certain symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Produced by macrophages, IFN-alpha have antiviral activities. 參考文獻
Henco K. et al., 1985, J Mol Biol. 185 (2): 227-60. Goeddel DV. et al., 1981, Nature. 290 (5801): 20-6. Yelverton E. et al., 1981, Nucleic Acids Res. 9 (3): 731-41. Kempaiah P. et al., 2012, Hum Genet. 131 (8): 1375-91. 規格:50ug 關 鍵 詞:Cynomolgus Interferon alpha-B / IFNA8 Protein,技術資料,價格,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
CANSPEC品質提供的Cynomolgus Interferon alpha-B / IFNA8 Protein|技術資料|價格性能**,其優良的品質滿足您不同實驗的多種需求。
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