Cynomolgus REG1A / PSPS Protein|使用說明|產品詳情

REG1A / PSPS蛋白產品信息

別名: REG1A
表達方式: 
A DNA sequence encoding the cynomolgus REG1A (G8F4F8) (Met1-Asn166) was expressed with a polyhistidine tag at the C-terminus.
種屬: Cynomolgus
表達宿主: Human Cells

REG1A / PSPS Protein QC Testing

純度: (55.6+42.8)% as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Gln 23
分子量: 
The recombinant cynomolgus REG1A comprises 155 amino acids and has a calculated molecular mass of 177 KDa. The apparent molecular mass of it is approximately 19 and 21 KDa respectively in SDS-PAGE.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

REG1A / PSPS Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

REG1A / PSPS蛋白背景綜述

Lithostathine-1-alpha, also known as Pancreatic stone protein, Pancreatic thread protein, Regenerating islet-derived protein 1-alpha, REG1A, REG-1-alpha, and PSPS, is highly expressed in fetal and infant brains. REG1A contains one C-type lectin domain and is a known growth factor affecting pancreatic islet beta cells. REG1A may act as an inhibitor of spontaneous calcium carbonate precipitation. It may also be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. REG1A has been reported to be expressed in human cancers, and it may be positively correlated with patient's prognosis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. High levels of REG1A expression by tumor cells are an independent predictor of a poor prognosis in patients with non-small cell lung cancer (NSCLC).

參考文獻

Gerbaud V. et al.,2000, J Biol Chem. 275: 1057-64.
Cavard C. et al., 2006, Oncogene. 25 (4): 599-608.
Astrosini C. et al., 2008, Int J Cancer. 123 (2): 409-13.
Minamiya Y. et al., 2008, Lung Cancer. 60 (1): 98-104.
Geng J. et al., 2009 Eur J Surg Oncol. 35 (8): 852-7.

規格：50ug

關 鍵 詞：Cynomolgus REG1A / PSPS Protein,使用說明,產品詳情，實驗室耗材，生化試劑，上海創賽，博飛美科，實驗儀器，廠家

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