Cynomolgus CD53 (aa 107-181) Protein|廠家|參數|價格

CD53蛋白產品信息

別名: CD53
表達方式: 
A DNA sequence encoding the cynomolgus CD53 (G7NW46) (Glu107-Asn181) was expressed with the Fc region of mouse IgG1 at the N-terminus.
種屬: Cynomolgus
表達宿主: Human Cells

CD53 Protein QC Testing

純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Asp
分子量: 
The recombinant cynomolgus CD53 is a disulfide-linked homodimer. The reduced monomer comprises 311 amino acids and has a calculated molecular mass of 34.9 KDa. The apparent molecular mass of it is approximately 44 KDa respectively in SDS-PAGE.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CD53 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CD53蛋白背景綜述

CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.

參考文獻

Rochelle JM. et al., 1993, Int Immunol. 5 (2): 209-16.
Virtaneva KI. et al., 1993, Immunogenetics. 37 (6): 461-5.
Horejsí V. et al., 1991, FEBS Lett. 288 (1-2): 1-4.

規格：50ug

關 鍵 詞：Cynomolgus CD53 (aa 107-181) Protein,廠家,參數,價格，實驗室耗材，生化試劑，上海創賽，博飛美科，實驗儀器，廠家

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