Cynomolgus NKG2A / NKG2 / CD159A / KLRC1 Protein|參數|廠家|價格

NKG2A / NKG2 / CD159A / KLRC1蛋白產品信息

別名: KLRC1
表達方式: 
A DNA sequence encoding the cynomolgus KLRC1 (Q9MZJ2) (Pro94-Leu233) was expressed with the Fc region of human IgG1 at the N-terminus.
種屬: Cynomolgus
表達宿主: Human Cells

NKG2A / NKG2 / CD159A / KLRC1 Protein QC Testing

純度: > 85 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Glu
分子量: 
The recombinant cynomolgus KLRC1 is a disulfide-linked homodimer. The reduced monomer comprises 400 amino acids and has a calculated molecular mass of 44.4 KDa.The apparent molecular mass of the protein is approximately 47-55 KDa respectively in SDS-PAGE.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

NKG2A / NKG2 / CD159A / KLRC1 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

NKG2A / NKG2 / CD159A / KLRC1蛋白背景綜述

NKG2, also known as NKG2A(CD159A), contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. NKG2 forms a complex with another family member, KLRD1/CD94. NKG2A and NKG2B appear to be splice variants of the same gene and have been given the designation CD159a in the nomenclature of CD antigens. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

參考文獻

Angelini DF et al., 2011, J Leukoc Biol. 89 (1): 75-84.
Ge SJ. et al., 2011, Zhongguo Shi Yan Xue Ye Xue Za Zhi. 19 (2): 312-6.
Ablamunits V. et al., 2011, Eur J Immunol. 41 (7): 1832-42.

規格：20ug

關 鍵 詞：Cynomolgus NKG2A / NKG2 / CD159A / KLRC1 Protein,參數,廠家,價格，實驗室耗材，生化試劑，上海創賽，博飛美科，實驗儀器，廠家

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