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    產品資料

    ICAM4 / CD242 Protein|廠家現貨|報價

    產品名稱: ICAM4 / CD242 Protein|廠家現貨|報價
    產品型號: C86-133-27
    產品展商: 博飛美科
    產品文檔: 無相關文檔

    簡單介紹

    ICAM4 / CD242 Protein|廠家現貨|報價由上海創賽科學儀器有限公司品質提供,可查詢ICAM4 / CD242 Protein價格。上海創賽科學儀器有限公司是專業**試劑生產及供應商,其優良的品質滿足您不同實驗的多種需求,歡迎撥打4006087598洽談選購,更多產品詳情請登錄www.getprovidencehotels.com


    ICAM4 / CD242 Protein|廠家現貨|報價  的詳細介紹

    ICAM4 / CD242蛋白產品信息

    別名: ICAM4, LW
    表達方式: 
    A DNA sequence encoding the human ICAM4 (NP_001034221.1) (Met1-Gly272) was expressed with the Fc region of human IgG1 at the C-terminus.
    種屬: Human
    表達宿主: Human Cells

    ICAM4 / CD242 Protein QC Testing

    純度: (50.3+36.1) % as determined by SDS-PAGE SDS-PAGE
    內**: < 1.0 EU per μg of the protein as determined by the LAL method
    穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
    預測N端: Ala 23
    分子量: 
    The recombinant human ICAM4/Fc is a disulfide-linked homodimer. The reduced monomer comprises 491 amino acids and has a predicted molecular mass of 54.4 kDa. The apparent molecular mass of the protein is approximately 55 and 33 kDa in SDS-PAGE under reducing conditions.
    緩沖液: Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    Please contact us for any concerns or special requirements.

    ICAM4 / CD242 Protein Usage Guide

    儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
    Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

    ICAM4 / CD242蛋白背景綜述

    ICAM4, also known as CD242, is a member of the?immunoglobulin superfamily, ICAM family. ICAM4 contains 2?Ig-like C2-type (immunoglobulin-like) domains. It is similar to the intercellular adhesion molecule (ICAM) protein family. ICAM4 binds to the leukocyte adhesion LFA-1 protein. ICAM4's first reported receptors were CD11a/CD18 and CD11b/CD18. ICAM4 functions as a ligand for the monocyte/macrophage-specific CD11c/CD18. Deletion of the individual immunoglobulin domains of ICAM4 demonstrated that both its domains contain binding sites for CD11c/CD18. CD11c/CD18 is expressed on macrophages in spleen and bone marrow. Inhibition of erythrophagocytosis by anti-ICAM4 and anti-integrin antibodies suggests a role for these interactions in removal of senescent red cells.

    參考文獻

    Gorst DW. et al., 1980, Vox Sanguinis. 38 (2): 99-105.
    Vos GH. et al., 1973, Blood. 42 (3): 445-53.
    Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
    Daniels G. et al., 2002, Transfusion Medicine. 12 (5): 287-95.

    規格:50ug

    關 鍵 詞:ICAM4 / CD242 Protein,廠家現貨,報價,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家

    CANSPEC品質提供的ICAM4 / CD242 Protein|廠家現貨|報價性能**,其優良的品質滿足您不同實驗的多種需求。

    本產品由上海創賽品質提供,歡迎咨詢國內免費服務專線:400-608-7598,更多產品信息請登錄www.getprovidencehotels.com 或 www.4006087598.com

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