FAM3C / ILEI蛋白產品信息
別名: FAM3C, ILEI 表達方式: A DNA sequence encoding the human FAM3C (Q92520)(Met1-Asp227) was expressed with the Fc region of human IgG1 at the C-terminus. 種屬: Human 表達宿主: Human Cells FAM3C / ILEI Protein QC Testing
純度: (73.6+19.1)% as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Gln 25 分子量: The recombinant human FAM3C/Fc is a disulfide-linked homodimer. The reduced monomer comprises 444 amino acids and has a predicted molecular mass of 49.2 kDa. The apparent molecular mass of the protein is approximately 53 and 35 kDa in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. FAM3C / ILEI Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. FAM3C / ILEI蛋白背景綜述
FAM3C, also known as ILEI, is a member of the FAM3 family. It can be detected in resent in most secretory epithelia. FAM3C may be involved in retinal laminar formation. It promotes epithelial to mesenchymal transition. A change in expression of FAM3C has been noted in pancreatic cancer-derived cells. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer. 參考文獻
Zhu Y. et al., 2002, Genomics. 80 (2): 144-50. Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903. Quéméner-Redon S. et al., 2003, Nature. 424 (6945): 157-64. 規格:50ug 關 鍵 詞:FAM3C / ILEI Protein,FAM3C / ILEI蛋白質,技術資料,現貨,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
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