Mouse IFNA14 / Interferon alpha-14 Protein|現貨促銷|價格

IFNA14 / Interferon alpha-14蛋白產品信息

別名: IFNA14
表達方式: 
A DNA sequence encoding the mouse IFNA14 (NP_996858.1)(Cys24-Lys189) was expressed with a C-terminal polyhistidine tag.
種屬: Mouse
表達宿主: Human Cells

IFNA14 / Interferon alpha-14 Protein QC Testing

純度: > 90 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Cys 24
分子量: 
The recombinant mouse IFNA14 comprises 177 amino acids and has a predicted molecular mass of 20.5 kDa. The apparent molecular mass of the protein is approximately 20 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

IFNA14 / Interferon alpha-14 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IFNA14 / Interferon alpha-14蛋白背景綜述

Interferon alpha-14, also known as Interferon alpha-H, IFN-alpha-14, LeIF H, Interferon lambda-2-H and IFNA14, is a secreted protein which belongs to the alpha/beta interferon family. IFNA14 is produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, or parasites or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs belong to the large class of glycoproteins known as cytokines. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection.

參考文獻

De Veer. et al., 2001,Journal of leukocyte biology. 69 (6): 912-20.
Liu YJ. et al., 2005, Annu Rev Immunol 23: 275-306.
Fensterl V. et al., 2009, Biofactors 35 (1): 14-20.

規格：100ug

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